Several drugs approved for insomnia are in the doghouse these days, and physicians are doing a fair amount of off-label prescribing. What medications should we expect to be prescribed in lieu of zolpidem (Ambien) and temazepam (Restoril)?
Using a “translational approach,” McGill University researchers have reviewed a host of medications with sedative properties and found the evidence base for some is stronger than for others. Here are the drugs they’ve found are most likely to work.
Antidepressants have been prescribed as de facto sleeping pills for over 3 decades now. This used to bother me. Most antidepressants have not been tested on people with simple insomnia and shown to improve their sleep.
These days I see things differently.
Some people I know are perfectly comfortable taking sleeping pills and would be happy to use them for the rest of their lives. Others say they’re harmful, having a raft of side effects and degrading the quality of sleep we get.
The pros and cons of sleeping pills are too numerous to explore in a blog (I do lay them out in The Savvy Insomniac, my book). But here’s a summary of the numbers of people using sleep meds in the US, which meds we’re using, and who’s using them.
Sleeping pills approved by the Food and Drug Administration–Ambien and Lunesta–are getting some negative press these days, and I hear more talk of using off-label medications to treat insomnia. (Off-label meds are drugs approved for the treatment of other disorders.) I’ve blogged about some of these drugs before: trazodone, clonazepam and quetiapine.
Pregabalin is another, which is now being prescribed for people with trouble waking up in the middle of the night.
Does your sleep problem involve waking up in the middle of the night once or several times and then trouble falling back to sleep? Sleep maintenance insomnia is actually the most common form of insomnia, and it’s more common as people age. Here’s a quick review of the possible causes and what can be done.
Trazodone has never been approved for the treatment of insomnia. Yet it rose to the top of the bestseller charts as a medication for sleeplessness in the 1990s and enjoys great popularity still. Here’s one explanation for its appeal.